Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0232PFAM: transport system permease protein; KEGG: mac:MA4605 iron(III) ABC transporter, permease protein. (346 aa)    
Predicted Functional Partners:
Pisl_0233
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mba:Mbar_A0509 iron compounds ABC transporter, ATP-binding protein.
 
 
 0.985
Pisl_0231
PFAM: periplasmic binding protein; KEGG: sth:STH1935 iron ABC transporter substrate-binding protein.
 
 
 0.962
Pisl_0214
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: chy:CHY_2191 iron compound ABC transporter, ATP-binding protein.
 
 
 0.928
Pisl_0227
PFAM: periplasmic binding protein; KEGG: fnu:FN0305 iron(III) dicitrate-binding protein.
 
 
 0.877
Pisl_0234
PFAM: nucleoside recognition domain protein; KEGG: mja:MJ1556 hypothetical protein.
  
    0.794
Pisl_0236
PFAM: nucleoside recognition domain protein; KEGG: mma:MM0124 hypothetical protein.
  
    0.794
Pisl_0235
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: mmp:MMP0874 SAM (and some other nucleotide) binding motif.
  
    0.782
Pisl_0059
PFAM: periplasmic binding protein; KEGG: pai:PAE3569 hypothetical protein.
 
 
 0.669
Pisl_0216
PFAM: periplasmic binding protein; KEGG: tte:TTE1869 ABC-type Fe3+-siderophores transport systems, periplasmic components.
 
 
 0.667
Pisl_1171
KEGG: pai:PAE0934 hypothetical protein.
  
 
 0.577
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (14%) [HD]