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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Pisl_0263Propionate CoA-transferase; PFAM: coenzyme A transferase; KEGG: pai:PAE2827 coA transferase, putative. (544 aa)    
Predicted Functional Partners:
Pisl_0813
KEGG: pai:PAE2183 acetyl-CoA C-acyltransferase.
    
 0.919
Pisl_1301
KEGG: pai:PAE1220 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase.
    
 0.919
Pisl_1437
PFAM: Thiolase; KEGG: pai:PAE1377 acetyl-CoA C-acyltransferase.
    
 0.919
Pisl_0218
PFAM: AMP-dependent synthetase and ligase; KEGG: pai:PAE2867 acetyl-coenzyme A synthetase.
    
 0.915
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.915
Pisl_0324
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: mth:MTH1740 pyruvate ferredoxin oxidoreductase, gamma subunit.
    
  0.902
Pisl_0498
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE3276 2-ketoacid ferredoxin oxidoreductase delta subunit.
    
  0.902
Pisl_1231
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE1041 pyruvate ferredoxin oxidoreductase delta subunit.
    
  0.902
Pisl_0325
Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: pai:PAE1042 pyruvate ferredoxin oxidoreductase alpha subunit.
     
  0.900
Pisl_0326
Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mja:MJ0266 pyruvate ferredoxin oxidoreductase, beta subunit.
     
  0.900
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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