Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0341PFAM: THUMP domain protein; KEGG: pai:PAE2935 hypothetical protein. (184 aa)    
Predicted Functional Partners:
tmcA
tRNA(Met)-cytidine N(4)-acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
 0.883
Pisl_0342
KEGG: pai:PAE2936 hypothetical protein.
       0.801
trm1
N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
   
 
 0.780
truD
Pseudouridylate synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
  
 
 0.734
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 
 0.720
Pisl_0347
KEGG: pai:PAE2941 hypothetical protein.
  
     0.599
Pisl_0340
KEGG: pai:PAE2934 hypothetical protein.
       0.579
Pisl_1565
PFAM: Protein of unknown function DUF1512; KEGG: pai:PAE1446 hypothetical protein.
  
     0.547
Pisl_0431
PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: pai:PAE3030 oligosaccharyl transferase STT3 homolog.
 
     0.546
Pisl_1398
PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: pai:PAE2792 conserved hypothetical protein part 1, authentic frameshift.
 
     0.495
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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