Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0342KEGG: pai:PAE2936 hypothetical protein. (195 aa)    
Predicted Functional Partners:
Pisl_1824
Bis(5'nucleosyl)-tetraphosphatase, ApaH; PFAM: metallophosphoesterase; SMART: serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase; KEGG: pai:PAE2004 serine/threonine specific protein phosphatase.
  
 0.917
Pisl_0341
PFAM: THUMP domain protein; KEGG: pai:PAE2935 hypothetical protein.
       0.801
Pisl_1436
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: pai:PAE1378 acyl-CoA dehydrogenase.
  
 0.746
Pisl_1853
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: pai:PAE2070 acyl-CoA dehydrogenase.
  
 0.746
Pisl_1964
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: pai:PAE2475 acyl-CoA dehydrogenase.
  
 0.746
Pisl_1671
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pai:PAE1650 enoyl-CoA hydratase, probable.
 
 0.615
Pisl_0567
Phosphoserine aminotransferase apoenzyme / L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: pai:PAE3321 aminotransferase (class 5).
 
 
 0.610
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.606
Pisl_0340
KEGG: pai:PAE2934 hypothetical protein.
       0.579
Pisl_1412
PFAM: peptidase S1 and S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; KEGG: pai:PAE2795 serine protease.
    
 0.552
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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