Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0347KEGG: pai:PAE2941 hypothetical protein. (206 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
       0.789
Pisl_0349
PFAM: tRNA-binding domain protein; KEGG: pai:PAE2942a methionyl-tRNA synthetase beta subunit.
       0.789
Pisl_0350
KEGG: pai:PAE2945 hypothetical protein.
       0.726
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
       0.714
Pisl_0351
KEGG: pai:PAE2946 hypothetical protein.
       0.714
Pisl_1565
PFAM: Protein of unknown function DUF1512; KEGG: pai:PAE1446 hypothetical protein.
  
     0.671
Pisl_2004
PFAM: protein of unknown function DUF343; KEGG: pai:PAE0284 hypothetical protein.
  
     0.633
Pisl_0341
PFAM: THUMP domain protein; KEGG: pai:PAE2935 hypothetical protein.
  
     0.599
Pisl_0508
KEGG: pai:PAE3262 hypothetical protein.
 
     0.552
Pisl_0913
TIGRFAM: LPXTG-motif cell wall anchor domain; KEGG: pai:PAE3088 oligopeptide binding protein, putative.
  
     0.541
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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