Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (238 aa)    
Predicted Functional Partners:
Pisl_1206
PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
 
 0.977
pyrH
Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.848
Pisl_0349
PFAM: tRNA-binding domain protein; KEGG: pai:PAE2942a methionyl-tRNA synthetase beta subunit.
  
  
 0.839
Pisl_1696
PFAM: peptidase M50; KEGG: pai:PAE1702 hypothetical protein.
 
  
 0.810
Pisl_0408
PFAM: putative RNA methylase; THUMP domain protein; KEGG: pai:PAE3215 hypothetical protein.
  
    0.797
Pisl_0347
KEGG: pai:PAE2941 hypothetical protein.
       0.789
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.763
Pisl_0549
PFAM: Polyprenyl synthetase; KEGG: pai:PAE3294 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.745
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
  
    0.735
Pisl_0350
KEGG: pai:PAE2945 hypothetical protein.
       0.726
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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