Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0372PFAM: protein of unknown function DUF354; KEGG: pai:PAE2970 hypothetical protein. (333 aa)    
Predicted Functional Partners:
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
       0.828
Pisl_0370
PFAM: Nucleotidyl transferase; KEGG: pai:PAE2968 sugar-phosphate nucleotidyl transferase, putative.
       0.789
Pisl_0373
KEGG: pai:PAE2971 hypothetical protein.
       0.696
Pisl_0496
PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: pai:PAE3281 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase, conjectural; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.545
Pisl_0369
paREP12; KEGG: pai:PAE1827 paREP12.
       0.524
Pisl_1112
PFAM: AMMECR1 domain protein; KEGG: pai:PAE0830 hypothetical protein.
 
     0.518
Pisl_0716
KEGG: pai:PAE0653 hypothetical protein.
  
     0.488
Pisl_1570
Serine O-acetyltransferase; KEGG: pai:PAE1472 acetyl/acyl transferase related protein.
 
    0.466
Pisl_1653
KEGG: pai:PAE1625 putative serine/threonine protein kinase.
  
     0.454
Pisl_0784
PFAM: glycosyl transferase, family 4; KEGG: pai:PAE3488 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase.
 
     0.439
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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