STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0484PFAM: CoA-binding domain protein; KEGG: pai:PAE3250 hypothetical protein. (461 aa)    
Predicted Functional Partners:
Pisl_0485
acetyl-CoA synthetase (ADP-forming) beta subunit; KEGG: pai:PAE3249 hypothetical protein.
 
 
 0.998
Pisl_0483
KEGG: pai:PAE3251 hypothetical protein.
       0.564
Pisl_1438
3-hydroxybutyryl-CoA epimerase; PFAM: protein of unknown function DUF35; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pai:PAE1383 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase.
  
    0.473
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: medium (46%) [HD]