Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
Pisl_0519Phosphoenolpyruvate synthase; PFAM: B3/4 domain protein; KEGG: pai:PAE3145 hypothetical protein. (221 aa)    
Predicted Functional Partners:
Pisl_0517
Putative circadian clock protein, KaiC; PFAM: KaiC domain protein; KEGG: pai:PAE3143 hypothetical protein; Belongs to the UPF0273 family.
       0.789
Pisl_0518
KEGG: pai:PAE3144 hypothetical protein.
       0.789
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.573
Pisl_0271
PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: pai:PAE2868 homoserine dehydrogenase.
       0.546
Pisl_0193
Transcriptional regulator, CopG family; KEGG: pab:PAB0960 putative nickel responsive regulator.
       0.538
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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