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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
Pisl_0601Gamma-glutamyltransferase 2, Threonine peptidase, MEROPS family T03; PFAM: gamma-glutamyltranspeptidase; KEGG: pai:PAE3371 gamma-glutamyltransferase. (462 aa)    
Predicted Functional Partners:
Pisl_1642
PFAM: HEAT domain containing protein; peptidase M1, membrane alanine aminopeptidase; PBS lyase HEAT domain protein repeat-containing protein; KEGG: pai:PAE1597 aminopeptidase.
  
 
 0.910
Pisl_0144
PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp; KEGG: pai:PAE2556 glutamine synthetase.
    
 0.837
Pisl_0980
Glutamate dehydrogenase (NAD); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: pai:PAE3438 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.836
Pisl_1816
PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: pai:PAE3438 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.836
Pisl_0400
Sulfide dehydrogenase (flavoprotein) subunit SudA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE3227 glutamate synthase small subunit.
    
 0.820
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
    
  0.812
Pisl_0602
PFAM: extracellular solute-binding protein, family 5; KEGG: pai:PAE2391 dipeptide binding protein.
     
 0.544
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.511
Pisl_1175
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE0939 2-oxoacid ferredoxin oxidoreductase alpha subunit.
     
 0.449
gatD
glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
 
  
 0.448
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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