Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Pisl_0628PFAM: protein of unknown function UPF0126; KEGG: pai:PAE2348 hypothetical protein. (208 aa)    
Predicted Functional Partners:
Pisl_0626
KEGG: pai:PAE2350 hypothetical protein.
       0.801
Pisl_0627
KEGG: pai:PAE2349 hypothetical protein.
       0.801
Pisl_0625
ABC transporter related protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; ABC transporter related; Possible metal-binding region in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: pai:PAE2352 RNase L inhibitor homolog.
       0.786
Pisl_0623
PFAM: glycosyl transferase, family 2; KEGG: pai:PAE2355 glycosyl transferase.
       0.699
Pisl_0624
KEGG: pai:PAE2354 hypothetical protein.
       0.699
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
       0.650
Pisl_0622
PFAM: CopG domain protein DNA-binding domain protein; KEGG: pai:PAE2357 hypothetical protein.
       0.487
Pisl_0621
KEGG: pai:PAE2358 hypothetical protein.
       0.420
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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