Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Pisl_0653Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein; KEGG: pai:PAE0731 transcriptional regulatory protein, conjectural. (73 aa)    
Predicted Functional Partners:
Pisl_1287
PFAM: ABC-3 protein; KEGG: pai:PAE1247 manganese transport permease protein.
  
  
 0.676
Pisl_0128
PFAM: periplasmic solute binding protein; KEGG: pai:PAE0564 putative zinc / manganese transport system substrate-binding protein.
  
  
 0.671
Pisl_1023
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: pai:PAE2309 ferric uptake regulator, putative.
  
  
 0.591
Pisl_0654
KEGG: pai:PAE0732 hypothetical protein.
       0.587
Pisl_2015
TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: pai:PAE0264 signal peptidase.
   
    0.527
Pisl_0009
PFAM: zinc/iron permease; KEGG: pai:PAE3636 zinc transporter, ZIP family.
  
  
 0.492
Pisl_1442
Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: pai:PAE2758 cation-transporting ATPase (P-type).
     
 0.484
rps7
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
       0.460
Pisl_0182
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sto:ST1066 hypothetical protein.
  
  
 0.433
Pisl_1288
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE1246 manganese ABC transporter ATP-binding protein.
  
  
 0.433
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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