Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Pisl_0660PFAM: regulatory protein, ArsR; KEGG: pai:PAE0738 transcriptional regulatory protein (helix-turn-helix), putative. (96 aa)    
Predicted Functional Partners:
Pisl_0659
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
       0.917
Pisl_0661
KEGG: pai:PAE0739 hypothetical protein.
       0.693
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
       0.592
Pisl_0658
KEGG: pai:PAE0736 hypothetical protein.
       0.590
Pisl_1091
KEGG: pai:PAE0799 molybdenum cofactor biosynthesis protein (moaC).
  
    0.582
rfcS1
Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.
       0.577
rps7
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
       0.500
Pisl_1442
Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: pai:PAE2758 cation-transporting ATPase (P-type).
  
  
 0.418
Pisl_0653
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein; KEGG: pai:PAE0731 transcriptional regulatory protein, conjectural.
  
  
 0.400
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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