Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0692Small nuclear ribonucleoprotein, LSM family; PFAM: Like-Sm ribonucleoprotein, core; SMART: Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core; KEGG: pai:PAE0676 small nuclear ribonucleoprotein homolog (Sm-like). (86 aa)    
Predicted Functional Partners:
mat
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
  
    0.923
rpl37e
LSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
  
  
 0.910
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
   
 0.908
rpoN
DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
  
 0.900
rpoH
DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
 
 0.880
hel308
DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
  
 0.877
rpl30e
PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: pai:PAE0668 ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family.
 
  
 0.870
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
 
    0.860
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
 0.835
eIF5A
Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
    0.834
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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