Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
atpASodium-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (593 aa)    
Predicted Functional Partners:
atpE
H+-transporting two-sector ATPase, E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.999
Pisl_0707
PFAM: Vacuolar H+-transporting two-sector ATPase, F subunit; KEGG: pai:PAE0661 H+-transporting ATP synthase subunit F (atpF).
  
 0.999
Pisl_1050
TIGRFAM: V-type ATPase, D subunit; PFAM: H+-transporting two-sector ATPase, D subunit; KEGG: pai:PAE0758 H+-transporting ATP synthase subunit D.
 
 0.999
Pisl_1052
PFAM: H+-transporting two-sector ATPase, C subunit; KEGG: pai:PAE0754 H+-transporting ATP synthase subunit C.
 
 0.999
Pisl_1053
KEGG: pai:PAE0753 H+-transporting ATP synthase subunit C.
  
 0.999
atpB
Sodium-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
 
0.999
Pisl_1725
PFAM: V-type ATPase, 116 kDa subunit; KEGG: pai:PAE1773 H+-transporting ATP synthase subunit I (atpI), conjectural; Belongs to the V-ATPase 116 kDa subunit family.
 
 0.999
Pisl_1737
KEGG: pai:PAE1773 H+-transporting ATP synthase subunit I (atpI), conjectural.
  
 0.982
Pisl_1054
KEGG: pai:PAE0752 hypothetical protein.
     
  0.900
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
 
  
 0.843
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.