Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0716KEGG: pai:PAE0653 hypothetical protein. (536 aa)    
Predicted Functional Partners:
Pisl_0717
KEGG: pai:PAE0652 hypothetical protein.
       0.801
Pisl_0715
KEGG: pai:PAE1488 hypothetical protein.
       0.761
tbp
TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
 
   
 0.649
Pisl_1008
PFAM: transcriptional regulator TrmB; KEGG: pai:PAE2282 hypothetical protein.
  
     0.615
Pisl_0674
PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: pai:PAE0712 surface layer-associated stable protease, conjectural; Belongs to the peptidase S8 family.
  
     0.569
Pisl_0127
PFAM: sodium/calcium exchanger membrane region; KEGG: pai:PAE0566 conserved within P.aerophilum.
  
     0.553
Pisl_0802
PFAM: metallophosphoesterase; KEGG: pai:PAE2243 hypothetical protein.
  
   
 0.536
Pisl_0913
TIGRFAM: LPXTG-motif cell wall anchor domain; KEGG: pai:PAE3088 oligopeptide binding protein, putative.
  
   
 0.536
Pisl_1466
PFAM: glycosyl transferase, group 1; KEGG: pai:PAE0540 glycosyltransferase (type 1).
 
     0.526
Pisl_0431
PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: pai:PAE3030 oligosaccharyl transferase STT3 homolog.
  
     0.512
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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