Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0718TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: pai:PAE0651 uracil DNA glycosylase (Pa-UDGa). (193 aa)    
Predicted Functional Partners:
Pisl_1921
PFAM: Uracil-DNA glycosylase superfamily; KEGG: pai:PAE1327 uracil-DNA glycosylase (Pa-UDGb).
  
  
 
0.906
Pisl_0719
KEGG: pai:PAE0649 hypothetical protein.
       0.582
Pisl_1089
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pai:PAE0797 short chain dehydrogenase.
       0.551
Pisl_0802
PFAM: metallophosphoesterase; KEGG: pai:PAE2243 hypothetical protein.
     
 0.477
Pisl_0716
KEGG: pai:PAE0653 hypothetical protein.
     
 0.476
Pisl_0720
paREP10; KEGG: pai:PAE0648 paREP10.
       0.475
Pisl_0739
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE0616 metallo cofactor biosynthesis protein.
      
 0.438
tbp
TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
      
 0.438
Pisl_0913
TIGRFAM: LPXTG-motif cell wall anchor domain; KEGG: pai:PAE3088 oligopeptide binding protein, putative.
      
 0.438
Pisl_1140
HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: pai:PAE0880 DNA-(apurinic or apyrimidinic site) lyase (endonuclease III, PaNth).
     
 0.436
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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