Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0736PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc; KEGG: pai:PAE0626 hypothetical protein. (114 aa)    
Predicted Functional Partners:
Pisl_0689
PFAM: protein of unknown function RIO1; KEGG: pai:PAE0680 RIO-like serine/threonine protein kinase.
   
 0.991
Pisl_0773
PFAM: protein of unknown function RIO1; KEGG: pai:PAE3474 RIO-type serine/threonine protein kinase.
   
 0.985
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
   
 
 0.956
rps11
SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
   
 0.947
rps4
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.947
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: pai:PAE3472 ribosomal protein S3; Belongs to the eukaryotic ribosomal protein eS1 family.
   
  0.943
rps7
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
   
 0.942
rps15
PFAM: ribosomal protein S15; Ribosomal S13S15-like; KEGG: pai:PAE3485 ribosomal protein S13.
   
  0.941
rps13
SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
    
  0.940
rps28e
PFAM: Ribosomal protein S28e; KEGG: pai:PAE3344 ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.
    
 0.933
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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