Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0749PFAM: band 7 protein; KEGG: pai:PAE0262 prohibitin homolog (HflK family). (340 aa)    
Predicted Functional Partners:
Pisl_1953
PFAM: peptidase M16 domain protein; KEGG: pai:PAE0368 protease.
  
 0.838
Pisl_0750
KEGG: pai:PAE0263 hypothetical protein.
       0.789
Pisl_1249
PFAM: Rhomboid family protein; KEGG: pai:PAE1099 integral membrane protein (rhomboid related), putative.
  
 0.690
Pisl_1247
PFAM: protein of unknown function DUF107; KEGG: pai:PAE1106 hypothetical protein.
  
 
 0.523
hflX
Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.506
Pisl_0577
PFAM: protein of unknown function, ATP binding; KEGG: pai:PAE3333 hypothetical protein.
   
 0.484
Pisl_1948
PFAM: protein of unknown function, ATP binding; KEGG: pab:PAB0955 hypothetical protein.
   
 0.484
Pisl_1056
Nodulation efficiency protein NfeD; PFAM: protein of unknown function DUF107; KEGG: pai:PAE0749 conserved protein (NfeD homolog).
  
  
 0.460
Pisl_1122
KEGG: pai:PAE0840 hypothetical protein.
  
 
 0.458
Pisl_1297
SMART: phospholipase D/Transphosphatidylase; KEGG: pai:PAE1226 DNA endonuclease, conjectural.
 
 0.450
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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