Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
psmB1Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (203 aa)    
Predicted Functional Partners:
psmA
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.919
psmB2
Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
  
 
0.907
Pisl_1835
KEGG: pai:PAE2024 hypothetical protein.
   
 0.884
Pisl_0958
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: pai:PAE2117 thermosome (chaperonin) alpha subunit.
 
 
 0.736
Pisl_0501
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: pai:PAE3273 thermosome (chaperonin) beta subunit.
 
 
 0.732
Pisl_0536
KEGG: pai:PAE3171 AAA family ATPase, possible cell division control protein cdc48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
 
 0.717
Pisl_0683
KEGG: pai:PAE0696 AAA family ATPase, possible cell division control protein cdc48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
 
 0.717
rpl4
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
 
 
 
 0.694
eIF5A
Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 0.679
Pisl_0659
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
  
  0.672
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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