Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0768PFAM: Radical SAM domain protein; KEGG: pai:PAE2255 hypothetical protein. (300 aa)    
Predicted Functional Partners:
Pisl_1674
NMD3; PFAM: NMD3; KEGG: pai:PAE1653 hypothetical protein.
  
     0.690
Pisl_1662
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: pai:PAE1638 putative transcriptional regulator.
  
     0.657
Pisl_0767
KEGG: pai:PAE2256 hypothetical protein.
       0.650
Pisl_0677
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE0707 hypothetical protein.
 
     0.606
Pisl_0769
KEGG: pai:PAE2254 hypothetical protein.
       0.586
Pisl_0244
KEGG: pai:PAE1234 hypothetical protein.
       0.567
Pisl_1696
PFAM: peptidase M50; KEGG: pai:PAE1702 hypothetical protein.
       0.547
Pisl_0690
PFAM: Protein of unknown function DUF460; KEGG: pai:PAE0678 hypothetical protein.
  
     0.540
Pisl_1809
Phosphoadenosine phosphosulfate reductase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; phosphoadenosine phosphosulfate reductase; KEGG: pai:PAE1989 hypothetical protein.
  
     0.534
Pisl_1844
PFAM: TatD-related deoxyribonuclease; KEGG: pai:PAE2050 hypothetical protein.
  
     0.502
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.