Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0773PFAM: protein of unknown function RIO1; KEGG: pai:PAE3474 RIO-type serine/threonine protein kinase. (266 aa)    
Predicted Functional Partners:
Pisl_0736
PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc; KEGG: pai:PAE0626 hypothetical protein.
   
 0.985
rps6e
PFAM: ribosomal protein S6e; KEGG: pai:PAE1505 ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
 
  0.959
rps11
SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.956
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.954
eif1a
Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
 
 0.948
rps4
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.944
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: pai:PAE3472 ribosomal protein S3; Belongs to the eukaryotic ribosomal protein eS1 family.
 
 
 0.935
Pisl_0689
PFAM: protein of unknown function RIO1; KEGG: pai:PAE0680 RIO-like serine/threonine protein kinase.
  
0.922
Pisl_0772
KEGG: pai:PAE3473 hypothetical protein.
 
  
 0.921
rps15
PFAM: ribosomal protein S15; Ribosomal S13S15-like; KEGG: pai:PAE3485 ribosomal protein S13.
 
  0.920
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.