Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0786PFAM: Miro domain protein; KEGG: pai:PAE3492 conserved within P.aerophilum. (161 aa)    
Predicted Functional Partners:
Pisl_0787
Conserved hypothetical protein; KEGG: pai:PAE3494 conserved within P.aerophilum.
       0.789
Pisl_1568
KEGG: pai:PAE1451 hypothetical protein.
  
     0.697
Pisl_1289
KEGG: pai:PAE1244 translation initiation factor aIF-2B subunit, conjectural; Belongs to the eIF-2B alpha/beta/delta subunits family.
  
     0.645
Pisl_1113
KEGG: pai:PAE0831 hypothetical protein.
  
     0.599
Pisl_0709
PFAM: zinc finger, C2H2-type domain protein; KEGG: pai:PAE0659 hypothetical protein containing 3 C2H2 zinc finger motifs.
  
     0.575
Pisl_0781
KEGG: pai:PAE3486 hypothetical protein.
       0.515
Pisl_0782
KEGG: pai:PAE3486 hypothetical protein.
       0.515
Pisl_0783
PFAM: deoxyhypusine synthase; KEGG: pai:PAE3487 deoxyhypusine synthase.
       0.515
Pisl_0784
PFAM: glycosyl transferase, family 4; KEGG: pai:PAE3488 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase.
       0.515
Pisl_0785
KEGG: pai:PAE3489 hypothetical protein.
       0.515
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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