Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0792KEGG: pai:PAE3499 hypothetical protein. (135 aa)    
Predicted Functional Partners:
cobB-2
PFAM: Silent information regulator protein Sir2; KEGG: pai:PAE3500 NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
       0.796
Pisl_0794
PFAM: peptidase S16, lon domain protein; KEGG: pai:PAE3507 hypothetical protein.
       0.534
Pisl_0766
KEGG: pai:PAE3573 hypothetical protein.
  
     0.500
Pisl_1612
PFAM: FAD dependent oxidoreductase; KEGG: pai:PAE1543 hypothetical protein.
  
     0.475
Pisl_0150
PFAM: ATPase; KEGG: pai:PAE2540 hypothetical protein.
  
     0.413
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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