Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
psmAProteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (251 aa)    
Predicted Functional Partners:
psmB1
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.919
psmB2
Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.916
Pisl_1835
KEGG: pai:PAE2024 hypothetical protein.
   
 0.884
rpl37ae
PFAM: ribosomal L37ae protein; KEGG: pai:PAE2202 ribosomal protein L37.
 
  
 0.868
Pisl_1751
PFAM: Ribosomal protein L15e; KEGG: pai:PAE1833 ribosomal protein L15.
 
  
 0.827
pfdB
Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 
 0.825
rpl4
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
 
 
 
 0.785
Pisl_0501
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: pai:PAE3273 thermosome (chaperonin) beta subunit.
 
 
 0.760
rrp42
Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
  
  
 0.753
rrp4
Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
     
 0.751
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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