Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0891PFAM: heat shock protein Hsp20; KEGG: pai:PAE2270 small heat shock protein, HSP20 homolog, conjectural; Belongs to the small heat shock protein (HSP20) family. (127 aa)    
Predicted Functional Partners:
Pisl_0537
PFAM: heat shock protein Hsp20; CS; KEGG: pai:PAE3172 small heat shock protein, HSP20 homolog, conjectural; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.960
Pisl_0144
PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp; KEGG: pai:PAE2556 glutamine synthetase.
   
 
 0.668
Pisl_0890
KEGG: pai:PAE2272 hypothetical protein.
       0.641
Pisl_1548
PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: mma:MM2421 chaperone protein.
  
 
 0.636
Pisl_0884
PFAM: SMC domain protein; KEGG: pai:PAE2280 hypothetical protein.
 
   
 0.558
Pisl_0889
PFAM: nitroreductase; KEGG: pai:PAE2273 reductase, putative.
  
  
 0.524
Pisl_0932
PFAM: peptidase M48, Ste24p; KEGG: pai:PAE3547 heat shock protein, HtpX homolog, conjectural.
 
  
 0.474
Pisl_1661
KEGG: pai:PAE1636 hypothetical protein.
  
     0.426
Pisl_0888
KEGG: pai:PAE2275 hypothetical protein.
       0.417
Pisl_0536
KEGG: pai:PAE3171 AAA family ATPase, possible cell division control protein cdc48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
  
 
 0.405
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.