Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Pisl_0903PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE3066 ABC-2 type transport system ATP-binding protein. (303 aa)    
Predicted Functional Partners:
Pisl_0902
PFAM: ABC-2 type transporter; KEGG: pai:PAE3065 ABC-2 type transport system, membrane protein.
  
  
 0.951
Pisl_0901
KEGG: pai:PAE3064 ABC-2 type transport system, membrane protein.
       0.831
Pisl_2013
PFAM: ABC-2 type transporter; KEGG: pai:PAE0270 membrane protein.
 
  
 0.710
Pisl_1969
PFAM: ABC-2 type transporter; KEGG: pai:PAE0316 ABC-2 type transport system, membrane protein.
  
  
 0.482
Pisl_1303
PFAM: transcriptional regulator PadR family protein; KEGG: pai:PAE1218 hypothetical protein.
 
  
 0.450
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.444
rpl2
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
   0.437
Pisl_0182
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sto:ST1066 hypothetical protein.
 
    0.433
Pisl_1019
KEGG: pai:PAE2297 valyl-tRNA synthetase.
 
 
 
 0.423
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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