Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Pisl_0904TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pai:PAE3068 phosphoglycolate phosphatase (pgp), conjectural. (197 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.742
Pisl_1967
PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: pai:PAE0318 hypothetical protein.
 
  
 0.671
Pisl_0788
SPP-like hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
  
 0.609
Pisl_0567
Phosphoserine aminotransferase apoenzyme / L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: pai:PAE3321 aminotransferase (class 5).
 
   
 0.607
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.536
Pisl_1061
Alpha-phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pai:PAE0764 phosphomannomutase (pmm); Belongs to the phosphohexose mutase family.
  
 
 0.534
Pisl_1645
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: sugar isomerase (SIS); KEGG: pai:PAE1610 hypothetical protein.
  
 
 0.453
pgk
PFAM: phosphoglycerate kinase; KEGG: pai:PAE1742 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.409
Pisl_1734
PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pai:PAE1785 hypothetical protein.
 
 
 0.400
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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