Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0916KEGG: pai:PAE3568 hypothetical protein. (244 aa)    
Predicted Functional Partners:
rpl10e
PFAM: Ribosomal protein L10E; KEGG: pai:PAE3567 ribosomal protein L10; Belongs to the universal ribosomal protein uL16 family.
       0.830
nac
Nascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.666
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.656
Pisl_0565
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; protein of unknown function UPF0074; Protein of unknown function DUF293; Helix-turn-helix, type 11 domain protein; KEGG: pai:PAE3319 conserved protein with 2 CBS domains.
       0.533
Pisl_0920
KEGG: pai:PAE3564 hypothetical protein.
       0.480
Pisl_0913
TIGRFAM: LPXTG-motif cell wall anchor domain; KEGG: pai:PAE3088 oligopeptide binding protein, putative.
       0.413
Pisl_0914
Hypothetical protein.
       0.413
Pisl_0915
Pullulanase; KEGG: pai:PAE3090 pullulanase.
       0.413
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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