Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0923PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc; KEGG: pai:PAE3561 hypothetical protein. (113 aa)    
Predicted Functional Partners:
Pisl_0772
KEGG: pai:PAE3473 hypothetical protein.
   
 0.976
Pisl_0402
rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: pai:PAE3232 nop family pre-rRNA processing protein.
   
 
 0.919
Pisl_0922
DNA-directed RNA polymerase, subunit E; PFAM: RNA binding S1 domain protein; RNA polymerase Rpb7-like; KEGG: pai:PAE3562 DNA-directed RNA polymerase subunit E'.
  
  
 0.853
Pisl_0574
snoRNP protein GAR1; KEGG: pai:PAE3330 hypothetical protein; involved in rRNA processing.
   
 
 0.850
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
 0.849
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 
 0.817
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
       0.812
nep1
Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
   
 0.807
Pisl_0924
KEGG: pai:PAE3560 hypothetical protein.
       0.801
Pisl_0925
PFAM: histidine triad (HIT) protein; KEGG: pai:PAE3559 HIT family protein.
       0.794
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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