Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0927KEGG: pai:PAE3556 hypothetical protein. (230 aa)    
Predicted Functional Partners:
Pisl_0928
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: pai:PAE3554 mannose-1-phosphate guanyltransferase.
       0.787
Pisl_0926
KEGG: pai:PAE3558 hypothetical protein.
       0.563
Pisl_0923
PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc; KEGG: pai:PAE3561 hypothetical protein.
       0.515
Pisl_0924
KEGG: pai:PAE3560 hypothetical protein.
       0.515
Pisl_0925
PFAM: histidine triad (HIT) protein; KEGG: pai:PAE3559 HIT family protein.
       0.515
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
       0.474
Pisl_0922
DNA-directed RNA polymerase, subunit E; PFAM: RNA binding S1 domain protein; RNA polymerase Rpb7-like; KEGG: pai:PAE3562 DNA-directed RNA polymerase subunit E'.
       0.474
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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