Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0928PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: pai:PAE3554 mannose-1-phosphate guanyltransferase. (359 aa)    
Predicted Functional Partners:
Pisl_1061
Alpha-phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pai:PAE0764 phosphomannomutase (pmm); Belongs to the phosphohexose mutase family.
  
 
 0.944
Pisl_1119
PFAM: Nucleotidyl transferase; KEGG: pai:PAE0837 sugar-phosphate nucleotidyl transferase.
  
  
 
0.918
Pisl_1489
PFAM: Nucleotidyl transferase; KEGG: pai:PAE2968 sugar-phosphate nucleotidyl transferase, putative.
  
  
 
0.915
Pisl_1490
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: afu:AF0044m GDP-D-mannose dehydratase (gmd-1).
    
 0.913
Pisl_1772
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: pai:PAE1922 UDP-glucose 4-epimerase.
 
 0.900
Pisl_1505
PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: afu:AF0596 UDP-glucose dehydrogenase.
  
 
 0.859
Pisl_1503
UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; KEGG: sso:SSO0813 UTP-glucose-1-phosphate uridylyltransferase.
 
  
0.841
Pisl_0433
PFAM: RNA binding S1 domain protein; Eukaryotic translation initiation factor 2, alpha subunit; KEGG: pai:PAE3032 translation initiation factor aIF-2 alpha subunit.
  
 0.821
Pisl_1289
KEGG: pai:PAE1244 translation initiation factor aIF-2B subunit, conjectural; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.813
Pisl_0427
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: pai:PAE3024 sugar-phosphate nucleotidyl transferase.
    
  0.801
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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