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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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surE-25'-nucleotidase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (253 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.985
pyrH
Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.928
Pisl_1197
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: pai:PAE0972 adenylosuccinate lyase.
    
 0.922
Pisl_1063
TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: pai:PAE0768 orotidine-5'-monophosphate decarboxylase.
    
 0.918
tmk
PFAM: thymidylate kinase; KEGG: pai:PAE0964 thymidylate kinase.
    
 0.918
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
 0.914
surE
3'-nucleotidase / 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
 
0.912
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.908
Pisl_1085
TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: pai:PAE0794 cytidine deaminase.
    
 0.905
Pisl_0389
PFAM: Quinolinate phosphoribosyl transferase; KEGG: pai:PAE2990 nicotinate phosphoribosyltransferase.
    
 0.904
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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