Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_09382,3-di-O-geranylgeranylglyceryl phosphate reductase; TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: pai:PAE2159 hypothetical protein. (453 aa)    
Predicted Functional Partners:
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
 
     0.839
Pisl_0939
PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase.
  
    0.831
Pisl_0941
SMART: AAA ATPase; KEGG: pai:PAE2155 conserved within P.aerophilum.
       0.799
Pisl_0647
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE0723 ferredoxin like protein.
 
 
 0.797
Pisl_0942
KEGG: pai:PAE2154 hypothetical protein.
       0.780
Pisl_0388
TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; KEGG: pai:PAE2989 hypothetical protein.
  
     0.721
Pisl_0228
Cobaltochelatase CobN subunit; PFAM: CobN/magnesium chelatase; KEGG: gvi:glr3328 magnesium protoporphyrin IX chelatase subunit H.
 
  
 0.629
Pisl_0229
Protoporphyrin IX magnesium-chelatase; KEGG: mhu:Mhun_0291 magnesium chelatase, ChlI subunit; PFAM: magnesium chelatase, ChlI subunit; von Willebrand factor, type A; SMART: AAA ATPase.
 
  
 0.592
Pisl_0732
KEGG: pai:PAE0634 hypothetical protein.
  
   
 0.583
Pisl_0646
PFAM: electron transfer flavoprotein beta-subunit; KEGG: pai:PAE0722 electron transfer flavoprotein beta subunit.
 
 
 0.506
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.