STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribKCTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (211 aa)    
Predicted Functional Partners:
Pisl_0687
FMN adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: pai:PAE0683 cytidyltransferase.
  
  
 0.932
Pisl_1833
TIGRFAM: riboflavin synthase; KEGG: pai:PAE2021 riboflavin synthase beta chain.
    
  0.920
Pisl_0938
2,3-di-O-geranylgeranylglyceryl phosphate reductase; TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: pai:PAE2159 hypothetical protein.
 
     0.832
Pisl_0939
PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase.
       0.792
Pisl_0941
SMART: AAA ATPase; KEGG: pai:PAE2155 conserved within P.aerophilum.
       0.791
Pisl_0942
KEGG: pai:PAE2154 hypothetical protein.
       0.784
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.691
Pisl_1337
Protein of unknown function DUF650; Involved in DNA damage repair.
  
     0.667
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
     0.655
Pisl_1660
PFAM: Protein of unknown function DUF373; KEGG: pai:PAE1635 hypothetical protein.
  
     0.654
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.