Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0941SMART: AAA ATPase; KEGG: pai:PAE2155 conserved within P.aerophilum. (456 aa)    
Predicted Functional Partners:
Pisl_0942
KEGG: pai:PAE2154 hypothetical protein.
       0.907
Pisl_0938
2,3-di-O-geranylgeranylglyceryl phosphate reductase; TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: pai:PAE2159 hypothetical protein.
       0.799
Pisl_0939
PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase.
       0.799
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
       0.799
Pisl_0299
KEGG: pai:PAE2902 hypothetical protein.
   
 
 0.767
Pisl_1851
KEGG: pai:PAE2059 hypothetical protein.
  
     0.505
Pisl_0884
PFAM: SMC domain protein; KEGG: pai:PAE2280 hypothetical protein.
 
   
 0.492
Pisl_0535
PFAM: CBS domain containing protein; KEGG: pai:PAE3169 conserved protein with 7 CBS domains.
 
     0.482
Pisl_0945
SMART: iron-sulfur cluster loop; KEGG: pai:PAE2138 hypothetical protein.
  
     0.481
Pisl_1287
PFAM: ABC-3 protein; KEGG: pai:PAE1247 manganese transport permease protein.
 
     0.472
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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