Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0957KEGG: pai:PAE2118 hypothetical protein. (181 aa)    
Predicted Functional Partners:
Pisl_0956
PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: pai:PAE2119 conjugal transfer protein, conjectural.
       0.793
Pisl_0955
PFAM: Zinc finger, TFIIB-type domain protein; Transcription factor TFIIB, cyclin-related; KEGG: pai:PAE2120 transcription initiation factor IIB, conjectural.
       0.787
Pisl_0954
KEGG: pai:PAE2121 hypothetical protein.
       0.549
Pisl_0953
PFAM: Like-Sm ribonucleoprotein, core; SMART: Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core; KEGG: pai:PAE2122 small nuclear ribonucleoprotein homolog (Sm-like).
       0.487
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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