Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0967PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: pai:PAE3430 glucose-1-phosphate adenylyltransferase. (407 aa)    
Predicted Functional Partners:
Pisl_0968
Glycogen synthase (ADP-glucose/UDP-glucose); PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: pai:PAE3429 glycogen synthase (starch (bacterial glycogen) synthase), putative.
 
   
 0.919
Pisl_0969
Alpha-amylase; PFAM: glycoside hydrolase, family 57; KEGG: pai:PAE3428 alpha-amylase.
     
 0.843
Pisl_1289
KEGG: pai:PAE1244 translation initiation factor aIF-2B subunit, conjectural; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.813
Pisl_0433
PFAM: RNA binding S1 domain protein; Eukaryotic translation initiation factor 2, alpha subunit; KEGG: pai:PAE3032 translation initiation factor aIF-2 alpha subunit.
  
 0.806
Pisl_0971
PFAM: glycosyl transferase, group 1; KEGG: pai:PAE3422 starch phosphorylase.
 
  
 0.723
Pisl_0370
PFAM: Nucleotidyl transferase; KEGG: pai:PAE2968 sugar-phosphate nucleotidyl transferase, putative.
  
     0.668
Pisl_0078
Translation initiation factor 2 subunit gamma (aeIF-2g); PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: pai:PAE0064 translation initiation factor aIF-2 gamma subunit, putative.
  
 0.544
Pisl_1723
PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: pai:PAE1764 GTP-binding protein.
  
 0.544
Pisl_1772
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: pai:PAE1922 UDP-glucose 4-epimerase.
 
 
 0.525
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
     0.492
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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