STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_0969Alpha-amylase; PFAM: glycoside hydrolase, family 57; KEGG: pai:PAE3428 alpha-amylase. (457 aa)    
Predicted Functional Partners:
Pisl_0971
PFAM: glycosyl transferase, group 1; KEGG: pai:PAE3422 starch phosphorylase.
 
 
 0.980
Pisl_1794
Alpha-glucosidase; PFAM: glycoside hydrolase, family 31; KEGG: pai:PAE1968 alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.
 
  
 0.930
Pisl_1316
KEGG: pai:PAE1209 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77.
    
  0.911
Pisl_0968
Glycogen synthase (ADP-glucose/UDP-glucose); PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: pai:PAE3429 glycogen synthase (starch (bacterial glycogen) synthase), putative.
 
  
 0.902
Pisl_0967
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: pai:PAE3430 glucose-1-phosphate adenylyltransferase.
     
 0.779
Pisl_0970
Tungsten-dependent formaldehyde:ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like; KEGG: pai:PAE3427 aldehyde ferredoxin oxidoreductase (aor).
       0.574
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.482
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.