Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0970Tungsten-dependent formaldehyde:ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like; KEGG: pai:PAE3427 aldehyde ferredoxin oxidoreductase (aor). (634 aa)    
Predicted Functional Partners:
Pisl_0738
PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like; KEGG: pai:PAE0622 aldehyde ferredoxin oxidoreductase.
  
  
 
0.912
Pisl_0971
PFAM: glycosyl transferase, group 1; KEGG: pai:PAE3422 starch phosphorylase.
       0.704
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.634
Pisl_0046
KEGG: pai:PAE0020 binding protein, putative.
 
   
 0.600
Pisl_0161
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE2860 molybdopterin oxidoreductase, iron-sulfur binding subunit.
  
 
 0.594
Pisl_0265
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE2837 molybdopterin oxidoreductase, iron-sulfur binding subunit.
  
 
 0.594
Pisl_1986
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: rxy:Rxyl_1613 4Fe-4S ferredoxin, iron-sulfur binding protein.
  
 
 0.594
Pisl_1995
Formate dehydrogenase beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE2661 formate dehydrogenase beta subunit.
  
 
 0.594
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
 
     0.592
Pisl_0968
Glycogen synthase (ADP-glucose/UDP-glucose); PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: pai:PAE3429 glycogen synthase (starch (bacterial glycogen) synthase), putative.
       0.573
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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