Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_0992TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: pai:PAE3466 molybdenum cofactor biosynthesis protein. (412 aa)    
Predicted Functional Partners:
Pisl_1190
TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: pai:PAE0969 molybdenum cofactor biosynthesis protein (moaB).
 
 0.979
Pisl_0984
Molybdenum cofactor guanylyltransferase; KEGG: pai:PAE3453 molybdopterin-guanine dinucleotide biosynthesis protein A.
 
 0.951
Pisl_0649
Molybdopterin synthase subunit MoaD / molybdopterin synthase subunit MoaE; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: pai:PAE0727 molybdenum cofactor biosynthesis protein D/E.
 
  
 0.931
Pisl_0991
Molybdopterin molybdochelatase; TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: pai:PAE3465 molybdenum cofactor biosynthesis protein.
 
  
 
0.923
Pisl_0445
PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; KEGG: pai:PAE3048 molybdenum cofactor biosynthesis protein.
  
  
 
0.918
Pisl_1779
KEGG: pai:PAE1934 hypothetical protein.
    
  0.907
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
 0.894
Pisl_1261
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pai:PAE1056 ThiF/MoeB/HesA family protein.
 
  
 0.592
Pisl_1716
TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: pai:PAE1759 molybdopterin-guanine dinucleotide biosynthesis protein B, conjectural.
  
 
 0.581
Pisl_0993
KEGG: pai:PAE3467 hypothetical protein.
       0.569
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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