Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1012PFAM: protein of unknown function DUF214; KEGG: pai:PAE2288 putative ABC transporter permease protein. (378 aa)    
Predicted Functional Partners:
Pisl_1011
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE2286 ABC transporter ATP-binding protein, putative.
 
 
 0.968
Pisl_1399
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE2785 ABC transporter ATP-binding protein, putative.
 
 
 0.877
Pisl_1010
KEGG: pai:PAE2285 hypothetical protein.
       0.799
Pisl_1013
KEGG: pai:PAE2290 membrane protein, putative.
   
   0.616
Pisl_1015
PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pai:PAE2293 hypothetical protein.
  
  
 0.478
Pisl_1014
KEGG: pai:PAE2291 hypothetical protein.
       0.434
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (8%) [HD]