Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Pisl_1069KEGG: pai:PAE0772 hypothetical protein. (507 aa)    
Predicted Functional Partners:
Pisl_1070
PFAM: type II secretion system protein E; KEGG: pai:PAE0773 conserved protein (possible type II secretion, gsp).
  
  
 0.911
Pisl_1403
PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: pai:PAE2778 type II secretion system protein, conjectural.
  
  
 0.825
Pisl_1068
TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: pai:PAE0771 N-acyltransferase.
       0.641
Pisl_1644
PFAM: peptidase A24A, prepilin type IV; KEGG: pai:PAE1599 hypothetical protein.
     
 0.513
Pisl_0868
KEGG: pai:PAE2399 type II secretion system protein, conjectural.
  
  
 0.512
Pisl_1071
KEGG: pai:PAE0776 hypothetical protein.
       0.466
Pisl_0407
ATPase, PilT family; PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: pai:PAE3216 hypothetical protein.
     
 0.445
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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