Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_1102PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pai:PAE0815 serine/threonine protein kinase, putative. (484 aa)    
Predicted Functional Partners:
Pisl_1603
PFAM: Dual specificity protein phosphatase; KEGG: pai:PAE1536 conserved protein (possible dual specificity phosphatase).
   
 0.925
Pisl_1548
PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: mma:MM2421 chaperone protein.
    
 0.915
Pisl_1824
Bis(5'nucleosyl)-tetraphosphatase, ApaH; PFAM: metallophosphoesterase; SMART: serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase; KEGG: pai:PAE2004 serine/threonine specific protein phosphatase.
 
 
 0.898
Pisl_0577
PFAM: protein of unknown function, ATP binding; KEGG: pai:PAE3333 hypothetical protein.
   
 0.894
Pisl_1948
PFAM: protein of unknown function, ATP binding; KEGG: pab:PAB0955 hypothetical protein.
   
 0.894
Pisl_1103
FHA domain containing protein; PFAM: Forkhead-associated protein; zinc finger, RanBP2-type; KEGG: pai:PAE0816 conserved protein with forkhead-associated (FHA) domain.
 
 
 
 0.868
Pisl_0536
KEGG: pai:PAE3171 AAA family ATPase, possible cell division control protein cdc48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
   
 0.832
Pisl_0683
KEGG: pai:PAE0696 AAA family ATPase, possible cell division control protein cdc48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
   
 0.832
Pisl_0381
PFAM: histone deacetylase superfamily; KEGG: pai:PAE2981 acetylpolyamine aminohydrolase, putative.
  
 
 0.819
Pisl_1089
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pai:PAE0797 short chain dehydrogenase.
  
 0.803
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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