Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_1105PFAM: protein of unknown function DUF52; KEGG: pai:PAE0818 conserved hypothetical protein; Belongs to the MEMO1 family. (281 aa)    
Predicted Functional Partners:
Pisl_1005
PFAM: AMMECR1 domain protein; KEGG: pai:PAE0745 hypothetical protein.
    0.984
rps2
PFAM: ribosomal protein S2; KEGG: pai:PAE0817 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
    0.901
Pisl_0542
PFAM: Radical SAM domain protein; KEGG: pai:PAE3184 pyruvate formate-lyase activating enzyme homolog.
     0.838
Pisl_0022
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE3672 pyruvate formate-lyase activating enzyme homolog.
     0.802
Pisl_1112
PFAM: AMMECR1 domain protein; KEGG: pai:PAE0830 hypothetical protein.
 
    0.664
rpl13
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
    0.627
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
    0.611
rps9
PFAM: ribosomal protein S9; KEGG: pai:PAE0674 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
    0.585
Pisl_1102
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pai:PAE0815 serine/threonine protein kinase, putative.
  
 
 0.579
rps11
SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
       0.567
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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