STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1105PFAM: protein of unknown function DUF52; KEGG: pai:PAE0818 conserved hypothetical protein; Belongs to the MEMO1 family. (281 aa)    
Predicted Functional Partners:
Pisl_1005
PFAM: AMMECR1 domain protein; KEGG: pai:PAE0745 hypothetical protein.
    0.983
rps2
PFAM: ribosomal protein S2; KEGG: pai:PAE0817 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.850
Pisl_0542
PFAM: Radical SAM domain protein; KEGG: pai:PAE3184 pyruvate formate-lyase activating enzyme homolog.
     0.828
Pisl_0022
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE3672 pyruvate formate-lyase activating enzyme homolog.
     0.804
Pisl_1112
PFAM: AMMECR1 domain protein; KEGG: pai:PAE0830 hypothetical protein.
 
    0.647
Pisl_0577
PFAM: protein of unknown function, ATP binding; KEGG: pai:PAE3333 hypothetical protein.
   
  0.623
Pisl_1948
PFAM: protein of unknown function, ATP binding; KEGG: pab:PAB0955 hypothetical protein.
   
  0.623
Pisl_1102
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pai:PAE0815 serine/threonine protein kinase, putative.
  
 
 0.594
Pisl_1103
FHA domain containing protein; PFAM: Forkhead-associated protein; zinc finger, RanBP2-type; KEGG: pai:PAE0816 conserved protein with forkhead-associated (FHA) domain.
  
    0.550
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
   
 0.498
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.