Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Pisl_1122KEGG: pai:PAE0840 hypothetical protein. (123 aa)    
Predicted Functional Partners:
cobS
Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
    0.770
Pisl_1056
Nodulation efficiency protein NfeD; PFAM: protein of unknown function DUF107; KEGG: pai:PAE0749 conserved protein (NfeD homolog).
  
  
 0.595
Pisl_1123
KEGG: pai:PAE0841 hypothetical protein.
       0.576
Pisl_0749
PFAM: band 7 protein; KEGG: pai:PAE0262 prohibitin homolog (HflK family).
  
 
 0.458
Pisl_1055
PFAM: band 7 protein; KEGG: pai:PAE0750 conserved protein (band 7 homolog).
  
 
 0.458
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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