STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1237PFAM: major facilitator superfamily MFS_1; KEGG: pai:PAE1049 hypothetical protein. (413 aa)    
Predicted Functional Partners:
Pisl_1236
PFAM: glycoside hydrolase, family 57; KEGG: pai:PAE1048 hypothetical protein.
       0.787
Pisl_1238
Cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pai:PAE1051 cysteine synthase.
 
   
 0.695
Pisl_1541
Hydrolase of the HD superfamily; KEGG: pai:PAE0109 hypothetical protein.
  
     0.644
Pisl_0674
PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: pai:PAE0712 surface layer-associated stable protease, conjectural; Belongs to the peptidase S8 family.
 
  
 0.577
Pisl_1994
Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: pai:PAE2662 formate dehydrogenase alpha subunit.
 
   
 0.573
Pisl_1661
KEGG: pai:PAE1636 hypothetical protein.
  
     0.552
Pisl_0015
KEGG: pai:PAE3644 hypothetical protein.
  
     0.549
Pisl_1113
KEGG: pai:PAE0831 hypothetical protein.
  
     0.536
Pisl_1320
KEGG: pai:PAE1173 hypothetical protein.
 
     0.515
Pisl_1544
TIGRFAM: CRISPR-associated RAMP protein, Csm3 family; PFAM: protein of unknown function DUF324; KEGG: pai:PAE0114 hypothetical protein.
  
     0.505
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.