Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_1671PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pai:PAE1650 enoyl-CoA hydratase, probable. (224 aa)    
Predicted Functional Partners:
Pisl_1437
PFAM: Thiolase; KEGG: pai:PAE1377 acetyl-CoA C-acyltransferase.
 
 0.977
Pisl_0813
KEGG: pai:PAE2183 acetyl-CoA C-acyltransferase.
 
 0.976
Pisl_0029
KEGG: pai:PAE3656 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase.
  
 0.965
Pisl_1301
KEGG: pai:PAE1220 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase.
  
 0.965
Pisl_1853
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: pai:PAE2070 acyl-CoA dehydrogenase.
 
 0.912
Pisl_1583
Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: pai:PAE1499 aconitate hydratase.
  
 0.910
Pisl_1436
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: pai:PAE1378 acyl-CoA dehydrogenase.
  
 0.899
Pisl_1964
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: pai:PAE2475 acyl-CoA dehydrogenase.
  
 0.899
Pisl_1412
PFAM: peptidase S1 and S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; KEGG: pai:PAE2795 serine protease.
 
 
 0.894
Pisl_1438
3-hydroxybutyryl-CoA epimerase; PFAM: protein of unknown function DUF35; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pai:PAE1383 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase.
  
 0.894
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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