Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1850KEGG: pai:PAE2058 hypothetical protein. (180 aa)    
Predicted Functional Partners:
Pisl_1849
KEGG: pai:PAE2056 hypothetical protein.
       0.688
Pisl_0649
Molybdopterin synthase subunit MoaD / molybdopterin synthase subunit MoaE; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: pai:PAE0727 molybdenum cofactor biosynthesis protein D/E.
       0.650
Pisl_0248
Vinylacetyl-CoA delta-isomerase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: pai:PAE2693 4-hydroxyphenylacetate-3-hydroxylase, conjectural.
  
  
 0.607
Pisl_1848
PFAM: protein of unknown function DUF59; KEGG: pai:PAE2055 hypothetical protein.
       0.515
Pisl_0386
PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; KEGG: pai:PAE2986 GTP cyclohydrolase II.
  
  
 0.440
Pisl_0636
PFAM: nitroreductase; KEGG: pai:PAE2336 hypothetical protein.
 
  
 0.427
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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