Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Pisl_1900PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: pai:PAE2445 ornithine cyclodeaminase (ArcB). (289 aa)    
Predicted Functional Partners:
Pisl_1901
DNA repair helicase RAD25; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pai:PAE2446 helicase, possible DNA repair.
       0.789
Pisl_1902
PFAM: protein of unknown function DUF790; KEGG: pai:PAE2447 hypothetical protein.
       0.789
Pisl_1899
KEGG: pai:PAE2442 hypothetical protein.
       0.717
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
 
 
   0.634
Pisl_1767
KEGG: pai:PAE1917 pyrroline-5-carboxylate reductase.
 
  
 0.533
Pisl_1898
PFAM: Abortive infection protein; KEGG: pai:PAE2439 conserved within P.aerophilum.
       0.517
Pisl_0897
Agmatinase; TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: pai:PAE2260 agmatinase; Belongs to the arginase family.
 
   
 0.476
Pisl_1024
PFAM: FAD dependent oxidoreductase; KEGG: pai:PAE2310 proline dehydrogenase.
 
  
 0.472
Pisl_0770
PFAM: aminotransferase, class I and II; KEGG: pai:PAE2251 aspartate aminotransferase (aspC), conjectural.
     
 0.466
Pisl_1238
Cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pai:PAE1051 cysteine synthase.
  
  
 0.445
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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